“They are similar in terms of the effects,” Dr Soni says, but rather than just providing hydration like hyaluronic acid skin boosters [such as Profhilo, Teoxane Redensity 1, Belotero Revive, and Sunekos Performa], polynucleotides communicate with the cells to make them produce collagen and elastin.

Also, “they work in all the areas many skin boosters can’t; like the eyes, lips, and forehead,” adds Dr Ward.

“They can be used effectively under the eyes, for the face and neck, and even for the jawline and cheekbones,” explains Dr Soni. “We do treatments for the face, neck, décolletage and body, including on scars and to stimulate hair growth,” adds Dr Esho, “but most requested is the eye area”.

It’s an animal product, so it’s not suitable for vegetarians, vegans or those with fish allergies. It’s also not appropriate for use during pregnancy or while breastfeeding. “I would not advocate someone too young getting the treatment either, unless there was something they were being specifically treated for,” adds Dr Soni. Otherwise, “the natural element of this treatment, and the fact that you can inject it into any type of anatomy, means that almost anyone is a candidate”.

“You start to see the results quite quickly after the first session,” says Dr Soni, “but the second session will really kickstart that remodelling process. The product continues to work for the first 12 weeks, so it continues to improve with time – however, you do get an improvement and lift early on after the first session.” The results last around six months on average before a patient would require one maintenance session at that point.